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Xofluza (80 MG Dose)® (Xofluza (80 MG Dose))

Taken just once, Xofluza (80 MG Dose) delivers the full flu treatment in a single oral dose, working differently than other antivirals. It's most effective within the first 48 hours of symptoms. After you book, your clinician reviews your history so your visit is about finding the right fit for you, whether that's Xofluza (80 MG Dose) or another option.

One dose is the entire treatment — no multi-day regimen

Works differently from Tamiflu — an alternative for those who need it

May reduce how long you're contagious to others

Visit options

We'll check any insurance and show you your options before you book.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Xofluza (80 MG Dose)?

Xofluza (80 MG Dose) is an antiviral medication that treats influenza A and B in people who have been symptomatic for 48 hours or less. What makes it distinct from other flu treatments like Tamiflu is how it works—rather than blocking the virus from spreading between cells, Xofluza (80 MG Dose) attacks an entirely different step in the viral replication process. It's taken as a single oral dose, making it one of the simplest antiviral regimens available. When taken early, it can shorten the duration of flu symptoms and reduce the risk of spreading the virus to others.

Cap-dependent endonuclease inhibition

Blocks a viral enzyme called cap-dependent endonuclease, preventing influenza from transcribing its genetic material inside host cells—an entirely different mechanism from other flu antivirals.

Single-dose treatment

The entire treatment course is one oral dose, eliminating the 5-day twice-daily regimen required by older antivirals and making it significantly easier to complete treatment correctly.

Viral load reduction

By halting viral replication at an early stage, Xofluza (80 MG Dose) rapidly reduces the amount of virus in the body—shortening symptom duration and potentially lowering the risk of transmitting flu to close contacts.

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently asked questions

How is Xofluza (80 MG Dose) different from Tamiflu?

Xofluza (80 MG Dose) works through a completely different mechanism than Tamiflu and requires only a single oral dose versus Tamiflu's 5-day twice-daily regimen. It may also reduce the period of viral shedding more rapidly.

Is one dose really enough?

Yes — one weight-based dose is the complete treatment for most patients. This removes the risk of forgetting follow-up doses and makes completing treatment significantly simpler than multi-day regimens.

How quickly does it work?

Like other flu antivirals, Xofluza (80 MG Dose) works best when taken within 48 hours of symptom onset. Symptom duration is typically shortened by 1–2 days when started early in the illness.

What side effects might I experience?

Xofluza (80 MG Dose) is generally well-tolerated. Diarrhea, nausea, headache, and bronchitis have been reported. Side effects are typically mild given the single-dose format and the short duration of drug exposure.

Can Xofluza (80 MG Dose) be used in children?

Yes. Xofluza (80 MG Dose) is approved for treatment of influenza in patients 5 years and older who have been symptomatic for less than 48 hours. Dosing is weight-based — your clinician will determine the appropriate amount.