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Vaxchora (Vibrio cholerae CVD 103-HGR strain live antigen)
Virtual visit

Vaxchora (Vibrio cholerae CVD 103-HGR strain live antigen)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Vaxchora (Vibrio cholerae CVD 103-HGR strain live antigen) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Vaxchora?

Vaxchora is an oral cholera vaccine taken as a single dose to protect adults traveling to areas where cholera is endemic or epidemic. It contains a live, attenuated (weakened) strain of Vibrio cholerae that can't cause disease but effectively stimulates the immune system. Unlike injectable vaccines, it works at the mucosal level—generating immune responses in the intestinal lining where cholera bacteria actually cause infection. The single-dose oral regimen makes it uniquely convenient, and protective immunity develops within 10 days of vaccination, lasting at least 3 months.

Live attenuated mucosal immunity

The weakened V. cholerae strain colonizes the intestinal tract briefly, stimulating both local IgA antibody production at the gut mucosa and systemic immune responses—training the immune system to recognize and neutralize real cholera toxin and bacteria.

Single-dose oral convenience

One packet dissolved in water provides the entire vaccination course—no injections, no multi-dose schedule—making it the most straightforward cholera prevention option available for travelers.

Rapid protection onset

Protective immunity develops within 10 days of the single dose, accommodating travelers who may have limited time before departure to regions with active cholera transmission.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

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What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

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Get the care you need, without the wait.

Frequently Asked Questions

Who should get the Vaxchora cholera vaccine?

Vaxchora is recommended for adults aged 18–64 traveling to areas where cholera is endemic or epidemic. The CDC and travel medicine clinicians can advise on specific destinations where the risk warrants vaccination.

How is Vaxchora taken?

Mix the contents of both foil pouches into the provided buffer solution, drink it as a single dose, and avoid eating or drinking for at least one hour before and after. The full dose is one drink — nothing else is required.

How far in advance of travel should I take Vaxchora?

Take it at least 10 days before potential exposure to allow adequate time for protective immunity to develop. Earlier vaccination is fine — protection develops within 10 days and lasts approximately 3–6 months.

Are there any side effects from Vaxchora?

Since it contains a live attenuated bacterial vaccine, mild GI symptoms — nausea, abdominal cramping, and diarrhea — can occur in some people. Fatigue and headache have also been reported. Effects are generally short-lived.

Can I take antibiotics around the time of Vaxchora vaccination?

No. Antibiotics kill the live bacteria in the vaccine and prevent an immune response from developing. Avoid antibiotics for at least 3 days before and during the vaccination process.
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