General MedicineGeneral Medicine
Varenicline

Varenicline

Without insurance

With insurance

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Varenicline?

Varenicline is a prescription medication specifically designed to help adults quit smoking. It works through a two-part mechanism: it partially stimulates nicotine receptors to ease withdrawal symptoms while simultaneously blocking nicotine from cigarettes from fully activating those same receptors. This means smoking becomes less satisfying even if you slip, while cravings and withdrawal feel more manageable throughout the process. Most people start Varenicline one week before their planned quit date and take it for 12 weeks, with the option to extend.

Partial receptor activation

Varenicline stimulates nicotine receptors just enough to reduce withdrawal symptoms like irritability, anxiety, and difficulty concentrating.

Nicotine blocking

By occupying nicotine receptors, Varenicline prevents cigarettes from delivering their usual reward — making slips less likely to derail your quit attempt.

Gradual craving reduction

Over the course of treatment, the urge to smoke typically decreases in both frequency and intensity as the brain's dependence on nicotine resets.

Virtual visit with clinician

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

Thousands of customers trust us

“I feel like I'm finally on the right path to improving my health with the right support now! It's so refreshing and reassuring.”

—Emerald, Texas

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

—Kaylee, Louisiana

“I couldn't be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

—Nika, Tennessee

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