General MedicineGeneral Medicine
Valacyclovir

Valacyclovir

Generic for Valtrex

Without insurance

With insurance

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is valacyclovir?

Valacyclovir is an antiviral medication used to treat and suppress herpes infections—including genital herpes, cold sores, shingles, and chickenpox. It's a prodrug of acyclovir, meaning the body converts it into acyclovir after absorption, achieving higher blood levels than acyclovir taken directly. Valacyclovir works by interfering with the herpes virus's ability to replicate its DNA inside infected cells. It can be taken episodically to shorten outbreaks or as daily suppressive therapy to reduce outbreak frequency and lower the risk of transmitting herpes to a partner.

Viral DNA replication inhibition

Valacyclovir is converted to acyclovir, which is then activated by a viral enzyme and incorporated into the virus's DNA chain — halting replication and preventing the virus from producing new infectious particles.

Prodrug bioavailability advantage

As a prodrug, valacyclovir achieves 3 to 5 times higher blood levels of acyclovir than oral acyclovir itself, allowing for less frequent dosing with better antiviral coverage.

Suppressive therapy option

Taken daily at a lower dose, valacyclovir reduces outbreak frequency by 70 to 80% and significantly lowers the risk of transmitting herpes to uninfected partners — making it a tool for both symptom management and transmission prevention.

Virtual visit with clinician

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

5 out of 5 stars on Trustpilot

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

5 out of 5 stars on Trustpilot

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

5 out of 5 stars on Trustpilot

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

5 out of 5 stars on Trustpilot

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

5 out of 5 stars on Trustpilot

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

5 out of 5 stars on Trustpilot

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

5 out of 5 stars on Trustpilot

Frequently asked questions

What is General Medicine?

What can General Medicine help with?

How much does General Medicine cost?

Who is the care team at General Medicine?

How do you protect my health information?