tTG-IgA test
Ongoing digestive symptoms like bloating or diarrhea are the most common reason to check. This test measures tTG-IgA, the primary antibody used to screen for celiac disease.
Reviewed by a licensed clinician, with results typically back in 1 to 2 days
Insurance accepted, with clear pricing options before you book
Flexible scheduling at your choice of nearby labs
Most insurance accepted
Board-certified clinicians
No hidden fees
Available nationwide
What is a Tissue Transglutaminase Antibody (IgA) Test?
Celiac disease screening
Elevated tTG-IgA is the primary blood-based indicator of celiac disease — reflecting the autoimmune response to gluten that causes progressive damage to the small intestinal lining. A positive result is strong evidence that further evaluation, including intestinal biopsy, is warranted.
Gluten exposure requirement for accuracy
tTG-IgA levels fall when gluten is removed from the diet — making it critical that patients consume a normal gluten-containing diet for at least 6 weeks before testing to avoid false negative results.
Treatment monitoring
After a confirmed celiac diagnosis and initiation of a gluten-free diet, declining tTG-IgA levels over time confirm that intestinal healing is occurring — providing objective evidence that dietary compliance is reducing the immune response.
Complete insights in days
1
Book your test
Instantly schedule at 2,000+ labs nationwide, at a time that works for you. Most visits take 15 minutes or less, with both walk-ins and appointments available.
2
Get clinician-reviewed results
Your results are delivered quickly—and reviewed by medical professionals. You’ll get clear explanations, robust health insights, and recommended next steps tailored to your health needs.
3
Take action with physician guidance
Choose to review your results and manage your plan with a General Medicine physician—or simply use the insights on your own.
4
Track progress over time
Repeat annually to see trends, improvements, and new emerging risks or book individual tests that focus on your set goals
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We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.
What's included
Test type
Blood sample
Collection method
Venipuncture
Fasting
Not required
Results processing time
1 to 2 days
tissue transglutaminase IgA antibody
Measures IgA antibodies against tissue transglutaminase (the main marker of celiac disease).
Ongoing support, always available.
You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.
Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.
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