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Tazarotene (Tazorac)
Virtual visit

Tazarotene (Tazorac)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Tazarotene (Tazorac) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Tazarotene (Tazorac)?

Tazorac is a prescription topical retinoid gel or cream used to treat plaque psoriasis and acne. It's one of the most potent topical retinoids available and works by binding to retinoic acid receptors in skin cells to normalize the abnormal cell turnover and differentiation that drives both conditions. For psoriasis, it reduces the rapid skin cell buildup that forms thick, scaly plaques. For acne, it unclogs pores by preventing the sticky follicular plugs that lead to comedones and breakouts. It's applied once daily in the evening and requires sunscreen use due to increased photosensitivity.

Retinoic acid receptor activation

Binds to RAR-β and RAR-γ receptors in skin cells, normalizing keratinocyte differentiation and proliferation—correcting the abnormal cell turnover that causes psoriatic plaques and acne-prone follicular plugging.

Psoriasis plaque reduction

Slows the excessive skin cell production in psoriasis and promotes more normal shedding, reducing the thickness, scaling, and inflammation of established plaques with consistent use.

Retinoid-grade acne clearance

As one of the strongest topical retinoids, Tazarotene effectively unclogs pores, reduces comedone formation, and improves inflammatory acne—often used for patients who haven't achieved adequate results with less potent retinoids like tretinoin or adapalene.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

How long before Tazorac improves acne or psoriasis?

For acne, meaningful improvement typically takes 8–12 weeks of consistent once-daily use. For psoriasis, plaque reduction may begin within 4 weeks, with continued improvement over the following months.

Why is Tazorac so irritating at first?

Retinoids accelerate skin cell turnover, which causes dryness, redness, and peeling in the first 2–6 weeks — particularly with a potent retinoid like tazarotene. Starting with every-other-night application can help the skin adjust.

Should I apply it in the morning or evening?

Evening application is generally recommended since tazarotene increases photosensitivity. If used in the morning, daily broad-spectrum sunscreen is essential. Applying to fully dry skin after cleansing reduces irritation.

What side effects might I experience?

Dryness, peeling, redness, burning, stinging, and worsening acne in the first weeks are very common. Using a gentle non-comedogenic moisturizer and avoiding other potentially irritating products helps manage early-stage reactions.

Is Tazorac safe during pregnancy?

No. Tazarotene is teratogenic — it can cause serious birth defects and is contraindicated in pregnancy. Effective contraception is required before and during treatment. Inform your clinician immediately if pregnancy occurs while using it.
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