Tadalafil

Without insurance

With insurance

Compare prices at 50K+ pharmacies nationwide

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Tadalafil?

Tadalafil is a prescription medication used to treat erectile dysfunction (ED) and, in some cases, benign prostatic hyperplasia (BPH)—an enlarged prostate that makes urination difficult. Like other PDE5 inhibitors, it works by increasing blood flow to specific tissues, but tadalafil is uniquely long-lasting, with effects that can last up to 36 hours. This gives it a more spontaneous quality compared to shorter-acting options. It can be taken as needed or as a lower daily dose for continuous readiness.

PDE5 inhibition

Blocks the enzyme that restricts blood flow in penile and prostate tissue, allowing smooth muscle to relax and circulation to improve when sexually stimulated.

36-hour window

Tadalafil's extended duration sets it apart—one dose can remain effective for up to a day and a half, reducing the need to time intimacy around medication.

Dual indication

At higher doses it treats ED; at lower daily doses it can also relieve urinary symptoms from an enlarged prostate, making it useful for men managing both conditions.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

Thousands of customers trust us

“I feel like I'm finally on the right path to improving my health with the right support now! It's so refreshing and reassuring.”

—Emerald, Texas

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

—Kaylee, Louisiana

“I couldn't be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

—Nika, Tennessee

Dive deeper: get the support you need

Your health rarely comes down to just one thing. If your clinician identifies related needs during your visit, we can help address them through additional services.

Medications

We will write your prescription and send it to your pharmacy

Lab tests

See cost up front and book your lab test instantly

Dermatology

Get a specialist consult or talk to a clinician about your condition

Travel needs

Going on a big trip? Get the vaccines and medications you need

Everyday care

No waitlist, rushed visits, or hidden fees—get care fast.

Frequently asked questions

What is General Medicine?

What can General Medicine help with?

General Medicine provides convenient care for all of your of health needs, including common and chronic conditions, specialist consultations, and preventative care. We make it easy to get the care you need—whether it's getting the right prescriptions, labs or imaging, or connecting you with the right specialists or in-person providers—ensuring your healthcare experience is seamless and stress-free.

How much does General Medicine cost?

Who is the care team at General Medicine?

How do you protect my health information?