General
Tadalafil (Cialis)
Virtual visit

Tadalafil (Cialis)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Tadalafil (Cialis) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Tadalafil (Cialis)?

Tadalafil is a prescription medication used to treat erectile dysfunction (ED) and, in some cases, benign prostatic hyperplasia (BPH)—an enlarged prostate that makes urination difficult. Like other PDE5 inhibitors, it works by increasing blood flow to specific tissues, but tadalafil is uniquely long-lasting, with effects that can last up to 36 hours. This gives it a more spontaneous quality compared to shorter-acting options. It can be taken as needed or as a lower daily dose for continuous readiness.

PDE5 inhibition

Blocks the enzyme that restricts blood flow in penile and prostate tissue, allowing smooth muscle to relax and circulation to improve when sexually stimulated.

36-hour window

Tadalafil's extended duration sets it apart—one dose can remain effective for up to a day and a half, reducing the need to time intimacy around medication.

Dual indication

At higher doses it treats ED; at lower daily doses it can also relieve urinary symptoms from an enlarged prostate, making it useful for men managing both conditions.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

How is Cialis different from Viagra or Levitra?

The key difference is duration. Cialis lasts up to 36 hours — significantly longer than Viagra or Levitra — allowing more spontaneous timing without needing to plan closely around when you take a dose.

Can I take Cialis every day?

Yes. A low daily dose (2.5–5 mg) provides continuous readiness rather than as-needed use. Daily dosing also helps manage urinary symptoms from an enlarged prostate in men who have both conditions.

Does it work the first time?

It works for many men on the first attempt, but some find it takes 2–3 tries. Anxiety, alcohol, and arousal level all influence how well it works — consistency helps establish what to expect.

What side effects might I experience?

Headache, back pain, muscle aches, flushing, and stuffy nose are most common. Back and muscle aches are more specific to tadalafil than other ED medications and typically resolve within 48 hours.

Is Cialis safe with blood pressure medications?

Depends on the specific medications. Tadalafil cannot be taken with nitrates. Your clinician will review your complete medication list before prescribing to ensure there are no dangerous interactions.
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