Cefixime

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What is Cefixime?

Cefixime is an oral third-generation cephalosporin antibiotic used to treat bacterial infections including uncomplicated urinary tract infections, otitis media (ear infections), pharyngitis and tonsillitis caused by Streptococcus pyogenes, and uncomplicated gonorrhea. It works by disrupting bacterial cell wall construction, causing bacteria to lyse and die. As a third-generation cephalosporin, it offers broader gram-negative coverage than earlier generations, making it effective against a wider range of pathogens. It can be taken once or twice daily depending on the infection being treated.

Beta-lactam cell wall disruption

Binds to penicillin-binding proteins and inhibits the cross-linking of peptidoglycan in bacterial cell walls, compromising their structural integrity and causing bacteria to lyse and die.

Third-generation gram-negative spectrum

Provides broader coverage against gram-negative bacteria than earlier cephalosporins—effective against pathogens including E. coli, Klebsiella, Proteus, and Neisseria gonorrhoeae that cause urinary, ear, and sexually transmitted infections.

Oral third-generation convenience

Delivers third-generation cephalosporin-level coverage in oral form, allowing outpatient treatment of infections that benefit from broader-spectrum antibiotics without requiring intravenous or intramuscular administration.

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