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Rescula (unoprostone) Eye Drops
Virtual visit

Rescula (unoprostone) Eye Drops

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Rescula (unoprostone) Eye Drops or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Rescula (unoprostone) Eye Drops?

Rescula is a prescription eye drop used to lower intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension—conditions where elevated pressure inside the eye can damage the optic nerve and lead to vision loss over time. Unoprostone is a docosanoid compound that works by increasing the outflow of aqueous humor from the eye, reducing the pressure that builds when fluid can't drain properly. It's applied twice daily and is typically used when other IOP-lowering medications haven't been sufficient on their own.

Aqueous humor outflow enhancement

Increases drainage of the fluid inside the eye through the uveoscleral and trabecular outflow pathways, reducing the intraocular pressure that can damage the optic nerve in glaucoma.

Docosanoid mechanism

Works through a different receptor pathway than prostaglandin analogs like latanoprost, giving it a distinct mechanism that can complement other IOP-lowering medications in patients who need additional pressure control.

Optic nerve pressure protection

By consistently lowering IOP, Rescula helps reduce the mechanical stress on the optic nerve that leads to progressive vision loss—the primary treatment goal in open-angle glaucoma management.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

What is Rescula used for?

Rescula eye drops are used to lower intraocular pressure in people with open-angle glaucoma or ocular hypertension — protecting the optic nerve from the pressure-related damage that leads to gradual vision loss.

How is Rescula different from other glaucoma drops like latanoprost?

Rescula works through a docosanoid pathway distinct from prostaglandin analogs like latanoprost or bimatoprost. This different mechanism makes it a useful add-on option when existing drops aren't providing enough pressure control.

How many times a day do I need to use Rescula?

Rescula is applied twice daily — morning and evening — to the affected eye(s). Consistent twice-daily dosing is important to maintain steady intraocular pressure reduction throughout the day.

What side effects might I experience?

Temporary stinging or burning after application, itching, redness, and dry eyes are most commonly reported. Eye color changes and eyelash growth changes — associated with some other glaucoma drops — are not characteristic of Rescula.

Can I use Rescula with other glaucoma eye drops?

Yes. Rescula is often used as an add-on when a single drop doesn't provide adequate pressure control. If using multiple eye drops, wait at least 5–10 minutes between applications to prevent dilution and washout.
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