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Relpax (eletriptan)
Virtual visit

Relpax (eletriptan)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Relpax (eletriptan) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Relpax (eletriptan)?

Relpax is a second-generation triptan medication taken at the onset of a migraine to stop the attack. It works by activating serotonin 5-HT1B and 5-HT1D receptors, causing constriction of dilated cranial blood vessels and blocking the release of inflammatory neuropeptides from trigeminal nerve endings that drive migraine pain. Compared to first-generation triptans, Eletriptan has a higher receptor affinity and better oral bioavailability, which may translate to faster and more reliable relief for some patients. It's taken as a single tablet and a second dose can be taken if the migraine returns after initial relief.

High-affinity serotonin receptor activation

Binds with greater affinity to 5-HT1B and 5-HT1D receptors than older triptans, producing potent cranial vasoconstriction and blocking the trigeminal inflammatory cascade that sustains migraine pain.

Improved oral bioavailability

Eletriptan's pharmacokinetic profile—with higher oral bioavailability than sumatriptan—results in more consistent drug absorption and potentially more reliable migraine relief across different patients and migraine types.

Second-dose option

If the migraine returns after initial relief, a second dose can be taken 2 hours after the first—providing a practical option for migraines that initially respond but subsequently recur within the same attack.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
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What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

How quickly does Relpax work for migraines?

Most people experience meaningful pain relief within 2 hours of taking Relpax. It's most effective when taken at the very first sign of a migraine — waiting until pain is severe significantly reduces its effectiveness.

How is Relpax different from first-generation triptans like sumatriptan?

Eletriptan has higher receptor affinity and better oral bioavailability than sumatriptan, which may translate to more consistent and reliable migraine relief — particularly for patients who've had unpredictable response to older triptans.

Can I take a second dose if my migraine returns?

Yes. If the migraine returns after initial relief, a second dose can be taken at least 2 hours after the first. No more than two doses should be used within any 24-hour period.

What side effects might I experience?

Dizziness, drowsiness, nausea, tingling, and a sensation of chest pressure or tightness are most common — typical of the triptan class. These are usually mild and brief. Serious chest symptoms require immediate medical evaluation.

Is Relpax safe with CYP3A4 inhibitors?

Relpax is metabolized by CYP3A4. Potent inhibitors of this enzyme — including certain antifungals, macrolide antibiotics, and HIV medications — can significantly increase eletriptan levels and should not be taken within 72 hours of Relpax.
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