General
PSA Total
Lab test

PSA Total

Recommended for men discussing prostate cancer screening, those with a prior elevated PSA, and men with known BPH or prostatitis who need ongoing monitoring. Avoid ejaculation and vigorous cycling for 48 hours before testing. Results are available within 2–4 days and reviewed by a General Medicine clinician.

Receive actionable insights and deep analysis—not just lab values– in as little as 48 hours

Clear guidance, and follow-up care available

Simple, online scheduling for labs and everything else

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is a PSA Total Test?

The PSA Total test measures the overall level of prostate-specific antigen in the blood — a protein produced exclusively by prostate tissue. PSA is elevated in prostate cancer, benign prostatic hyperplasia (BPH), and prostatitis, making it the primary and most widely used screening marker for prostate health and an essential tool for monitoring known prostate conditions.

Prostate cancer screening

Elevated total PSA is the main blood-based signal for possible prostate cancer. While not diagnostic on its own, a rising or elevated PSA prompts further evaluation — including free PSA ratio, repeat testing, and potentially biopsy — that allows early detection when treatment is most effective.

BPH and prostatitis monitoring

PSA is also elevated in benign prostate enlargement and prostate infection, which are far more common than cancer. PSA Total helps monitor these conditions over time, guiding treatment decisions and distinguishing worsening benign disease from cancer-related change.

Post-treatment surveillance

For men treated for prostate cancer — with surgery, radiation, or other therapy — PSA Total is the primary marker for confirming treatment success and detecting early signs of recurrence before it becomes clinically apparent.

Complete insights in as little as 48 hours

1

Book your test

Instantly schedule at 2,000+ labs nationwide, at a time that works for you. Most visits take 15 minutes or less, with both walk-ins and appointments available.

2

Get results in 48 hours

Your results are delivered quickly—and reviewed by medical professionals. You’ll get clear explanations, robust health insights, and recommended next steps tailored to your health needs.

3

Take action with physician guidance

Choose to review your results and manage your plan with a General Medicine physician—or simply use the insights on your own.

4

Track progress over time

Repeat annually to see trends, improvements, and new emerging risks or book individual tests that focus on your set goals

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What's included

Test type

Blood sample

Collection method

Venipuncture

Fasting

Not required

Results processing time

1 to 2 days

PSA (Prostate-Specific Antigen)

Reflects prostate gland health and can signal possible prostate cancer or other prostate conditions.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

What our customers have to say

Hear from people who felt heard, understood, and supported on General Medicine.

“I found the ease of setting the appointment and how quickly I was able to be seen to be amazing. The physician was very friendly and amazingly helpful.”

Natalie, Texas

“The chat visit was super convenient. The doctor was friendly and took the time needed to answer any questions I had. The prescription I needed was called in and ready the same afternoon.”

Dustin, Tennessee

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Ann, Florida

“General Medicine is easily the most approachable, efficient, high-quality, and responsive care team I've had the pleasure of working with.”

John, Utah

“General Medicine helped me get the imaging and blood work I needed, referred me to the right specialists, and even helped me find a new family doctor.”

Bridget, Mississippi

Order your lab today.

Frequently asked questions

What does a total PSA test measure?

PSA (prostate-specific antigen) is a protein produced by the prostate gland. Total PSA is elevated in prostate cancer, benign prostatic hyperplasia (BPH), and prostatitis. It's used as a screening marker and to monitor known prostate disease or treatment response.

What PSA level is considered abnormal?

There is no single cutoff that applies to everyone — interpretation depends on age, prostate size, and PSA trends over time. Generally, PSA above 4.0 ng/mL warrants further evaluation, but a rising PSA trend or rapidly increasing velocity can be significant even within the normal range.

Should I avoid anything before getting a PSA test?

Yes — ejaculation, vigorous cycling, and prostate examination or procedures can transiently elevate PSA and should be avoided for at least 48 hours before testing. Active urinary tract infection or prostatitis also raises PSA — testing should be postponed until infection resolves.

Can I have prostate cancer with a normal PSA?

Yes — a small percentage of prostate cancers, including some aggressive ones, occur with PSA in the normal range. PSA is a screening tool with real limitations. A normal result reduces but does not eliminate concern. Clinical examination and free-to-total PSA ratio add important context.

At what age should men start PSA screening?

Average-risk men should discuss PSA screening starting at age 50. Black men and those with a first-degree relative diagnosed with prostate cancer before age 65 should consider discussing screening at age 40–45, as their risk is meaningfully higher.
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