Pristiq

Brand for desvenlafaxine

Without insurance

With insurance

Compare prices at 50K+ pharmacies nationwide

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Pristiq?

Pristiq is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder. Affecting both serotonin and norepinephrine, rather than serotonin alone, can make it an option when an SSRI hasn't been fully effective. It's taken once daily in an extended-release form, and like other antidepressants, full effect builds over several weeks.

Dual neurotransmitter effect

Affects both serotonin and norepinephrine, a broader mechanism than a typical SSRI.

Extended-release formulation

An extended-release tablet taken once daily, releasing the medication steadily over the day for consistent symptom coverage.

Gradual improvement

Full antidepressant effect builds gradually over several weeks of consistent use, similar to most other antidepressants.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

Thousands of customers trust us

“I feel like I'm finally on the right path to improving my health with the right support now! It's so refreshing and reassuring.”

—Emerald, Texas

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—Kaylee, Louisiana

“I couldn't be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

—Nika, Tennessee

Dive deeper: get the support you need

Your health rarely comes down to just one thing. If your clinician identifies related needs during your visit, we can help address them through additional services.

Medications

We will write your prescription and send it to your pharmacy

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Everyday care

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General Medicine provides convenient care for all of your of health needs, including common and chronic conditions, specialist consultations, and preventative care. We make it easy to get the care you need—whether it's getting the right prescriptions, labs or imaging, or connecting you with the right specialists or in-person providers—ensuring your healthcare experience is seamless and stress-free.

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