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Phexxi (Lactate - citric acid - potassium bitartrate)
Virtual visit

Phexxi (Lactate - citric acid - potassium bitartrate)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Phexxi (Lactate - citric acid - potassium bitartrate) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Phexxi?

Phexxi is a prescription non-hormonal vaginal contraceptive gel applied immediately before sex to prevent pregnancy. It works by maintaining the natural acidic pH of the vagina—which typically rises during sex due to the alkalinity of semen—creating an environment that immobilizes and kills sperm before they can reach and fertilize an egg. It contains a combination of lactic acid, citric acid, and potassium bitartrate that acts as a buffering system to maintain vaginal acidity. Used as directed (one applicator inserted up to one hour before each act of intercourse), it's about 86% effective with typical use.

Vaginal pH maintenance

The acidic buffering agents in Phexxi prevent semen from raising vaginal pH to the alkaline level that sperm require for motility and survival—maintaining an acidic environment that is hostile to sperm function.

Sperm immobilization

By keeping vaginal pH low during and after sex, Phexxi impairs sperm motility and reduces their ability to navigate through the reproductive tract to reach an egg—providing contraceptive effect through a physiological mechanism.

On-demand non-hormonal option

Phexxi is used only when needed—applied up to one hour before intercourse—with no daily regimen, no hormonal effects on mood or cycle, and no systemic absorption, making it a targeted choice for women who want hormone-free contraception.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

How effective is Phexxi at preventing pregnancy?

Phexxi is about 86% effective with typical use — less effective than hormonal contraceptives or IUDs. It's most appropriate for people seeking non-hormonal contraception who understand and accept this effectiveness level.

Does Phexxi protect against sexually transmitted infections?

No. Phexxi does not provide STI protection. Condoms should be used alongside Phexxi if STI prevention is also needed.

How far in advance can I apply Phexxi?

Apply Phexxi no more than one hour before sex. It works by maintaining vaginal acidity during intercourse — timing is important for effectiveness. If more than one hour passes before sex, reapply a new dose.

What side effects might I experience?

Vaginal burning, itching, and discomfort are the most commonly reported effects — both for the user and potentially their partner. These are usually mild and temporary. Urinary tract symptoms can also occur.

Can Phexxi be used alongside hormonal birth control?

Yes. Phexxi can be used as additional contraceptive coverage alongside any hormonal method, IUD, or condoms. It doesn't interact with hormonal contraceptives and can be used to add a layer of protection when desired.
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