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Odactra (American house dust mite allergenic extract - European house dust mite allergenic extract)
Virtual visit

Odactra (American house dust mite allergenic extract - European house dust mite allergenic extract)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Odactra (American house dust mite allergenic extract - European house dust mite allergenic extract) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Odactra?

Odactra is a prescription sublingual immunotherapy tablet used to treat house dust mite-induced allergic rhinitis in adults. Unlike allergy shots that require office visits, Odactra is taken as a daily dissolving tablet placed under the tongue at home—making it a more convenient form of allergen immunotherapy. It contains standardized extracts of both American and European house dust mites, the two species most responsible for indoor allergies. Odactra gradually desensitizes the immune system to dust mite allergens over time, reducing the severity of allergic symptoms with sustained daily use. The first dose is taken in a medical setting due to the risk of allergic reactions.

Sublingual allergen desensitization

Delivers standardized dust mite extract to immune cells under the tongue—where the oral mucosa contains tolerogenic dendritic cells—gradually reprogramming the immune response from allergic reactivity toward tolerance.

At-home immunotherapy

Unlike subcutaneous allergy shots that require clinic visits, Odactra is taken as a once-daily dissolving tablet at home after the first supervised dose—dramatically improving accessibility and convenience for patients pursuing allergen immunotherapy.

Dual mite species coverage

Contains both Dermatophagoides farinae (American) and Dermatophagoides pteronyssinus (European) house dust mite extracts—the two most clinically relevant species—providing comprehensive desensitization across the dominant dust mite allergens.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
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What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

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Get the care you need, without the wait.

Frequently Asked Questions

How is Odactra different from allergy shots?

Odactra is a daily dissolving tablet taken under the tongue at home — after the first supervised dose in a medical setting. Allergy shots require regular clinic visits. Both use allergen immunotherapy but through different delivery routes.

How long before Odactra reduces my dust mite allergy symptoms?

Clinical trials showed meaningful symptom reduction over the first allergy season of treatment. Like all immunotherapy, Odactra requires sustained use over months to build lasting desensitization.

Why must the first dose be given in a medical setting?

The first dose carries a risk of allergic reaction including anaphylaxis. After the first dose is tolerated under medical supervision, subsequent doses can be safely taken at home.

What side effects might I experience?

Oral itching, tingling, throat irritation, and ear itching are commonly reported in the first weeks — reflecting the immune response at the site of sublingual delivery. These typically diminish as treatment continues.

How long do I need to take Odactra?

Treatment is typically recommended for at least 3 years to achieve durable allergy desensitization that persists after stopping. Shorter courses provide less lasting benefit. Your clinician will reassess response over time.
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