General
NovoLog Mix (Insulin aspart protamine - insulin aspart)
Virtual visit

NovoLog Mix (Insulin aspart protamine - insulin aspart)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for NovoLog Mix (Insulin aspart protamine - insulin aspart) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is NovoLog Mix?

NovoLog Mix is a combination insulin product that blends rapid-acting insulin aspart with intermediate-acting insulin aspart protamine in a fixed ratio—most commonly 70% intermediate-acting and 30% rapid-acting. This combination provides both immediate coverage for mealtime blood sugar spikes and extended background insulin action, making it a convenient option for people who prefer fewer injections than a full basal-bolus regimen requires. It's injected subcutaneously twice daily, typically before breakfast and dinner, and must be mixed by rolling the pen before each use.

Dual-phase insulin action

The rapid-acting component begins working within 10–20 minutes to cover post-meal glucose spikes, while the intermediate-acting protamine suspension provides extended background insulin coverage lasting 10–16 hours.

Simplified injection schedule

Combines mealtime and basal insulin coverage into twice-daily injections, reducing the number of daily shots compared to a separate basal-bolus regimen while still providing meaningful glucose control across the day.

Pre-mixed fixed ratio

The 70/30 formulation delivers a consistent, predictable blend—important to maintain through proper pen-rolling technique before each injection to ensure the suspension is uniformly mixed before dosing.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

How is NovoLog Mix different from regular NovoLog?

NovoLog Mix combines rapid-acting insulin aspart with intermediate-acting insulin aspart protamine in a fixed ratio — providing both mealtime coverage and extended background insulin in a single injection, unlike regular NovoLog which is rapid-acting only.

How many injections per day does NovoLog Mix require?

NovoLog Mix is typically injected twice daily — before breakfast and before dinner. This is fewer injections than a full basal-bolus regimen, which is one of its practical advantages for some patients.

Do I need to mix the pen before injecting?

Yes. Roll the pen between your palms at least 10 times and tip it gently 10 times before each injection to ensure the suspension is uniformly mixed. Do not shake — it should look uniformly cloudy, not clear.

What side effects might I experience?

Hypoglycemia (low blood sugar) is the primary risk — symptoms include shakiness, sweating, confusion, and rapid heartbeat. Injection site reactions can occur with repeated use in the same area. Rotate sites consistently.

Can I mix NovoLog Mix with other insulins?

No. Pre-mixed insulins like NovoLog Mix should not be mixed with other insulin formulations. Use it exactly as prescribed and do not attempt to combine it with basal or other rapid-acting insulins in the same syringe.
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