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Neupro (Rotigotine)
Virtual visit

Neupro (Rotigotine)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Neupro (Rotigotine) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Neupro (Rotigotine)?

Neupro is a transdermal patch delivering rotigotine—a dopamine agonist—continuously through the skin over 24 hours. It's used to treat Parkinson's disease and moderate-to-severe restless legs syndrome (RLS). For Parkinson's, it helps compensate for the loss of dopamine-producing neurons by stimulating the dopamine receptors those neurons would normally activate. For RLS, it reduces the uncomfortable urge-to-move sensations in the legs that disrupt rest and sleep. The patch is applied once daily to a different skin site each day, providing stable, consistent drug delivery without the peaks and troughs of oral dosing.

Continuous dopamine receptor stimulation

Rotigotine activates D2, D3, and D1 dopamine receptors continuously through transdermal delivery, compensating for reduced dopamine signaling in Parkinson's disease and modulating the spinal pathways implicated in restless legs syndrome.

Steady-state transdermal delivery

Unlike oral dopaminergic medications that create fluctuating drug levels, the patch provides smooth, consistent 24-hour drug exposure—reducing the on-off motor fluctuations that can develop with oral Parkinson's treatments.

Once-daily patch convenience

A single patch applied each morning delivers medication around the clock without the need for multiple daily doses—improving adherence and providing consistent symptom control throughout the day and overnight.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

How do I apply the Neupro patch correctly?

Apply to clean, dry, intact skin on the shoulder, upper arm, abdomen, thigh, or hip. Rotate application sites daily. Press firmly for 30 seconds to ensure full adhesion and avoid the same site for 14 days.

How long before Neupro improves Parkinson's or RLS symptoms?

For restless legs syndrome, improvement may be noticed within the first week. For Parkinson's disease, meaningful benefit develops over several weeks as the dose is gradually increased to the optimal level.

What happens if the patch falls off?

Apply a new patch to a different site for the remainder of that day's wear period. Continue on the original schedule the following day. Never apply two patches at the same time to compensate.

What side effects might I experience?

Application site reactions — redness, itching, and irritation — are the most common. Nausea, dizziness, drowsiness, and in some cases sudden onset of sleep (sleep attacks) can occur, particularly when driving.

Can Neupro cause compulsive behaviors?

Yes. Dopamine agonists including rotigotine have been associated with impulse control disorders — including compulsive gambling, eating, or spending. Report any unusual behavioral changes to your clinician promptly.
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