General
Nebivolol (Bystolic)
Virtual visit

Nebivolol (Bystolic)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Nebivolol (Bystolic) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Nebivolol (Bystolic)?

Bystolic is a prescription beta-blocker used to treat high blood pressure. It's a highly selective beta-1 blocker—meaning it primarily targets receptors in the heart rather than those in the lungs—making it better tolerated than older, less selective beta-blockers in patients with respiratory conditions. Nebivolol also has a unique vasodilating property mediated through nitric oxide release, which further lowers blood pressure and reduces cardiac workload. Taken once daily, it slows heart rate, reduces the force of cardiac contractions, and relaxes blood vessels to bring blood pressure down.

Highly selective beta-1 blockade

Targets beta-1 adrenergic receptors in the heart with high selectivity, slowing heart rate and reducing cardiac output—with less effect on beta-2 receptors in the airways than older, non-selective beta-blockers.

Nitric oxide-mediated vasodilation

Uniquely among beta-blockers, Nebivolol stimulates endothelial nitric oxide production, causing blood vessel relaxation and additional blood pressure reduction beyond what beta-blockade alone achieves.

Once-daily cardiac protection

Provides consistent 24-hour blood pressure control while also reducing myocardial oxygen demand—a combination that makes beta-blockers like Bystolic particularly valuable for hypertensive patients with coexisting heart disease.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

How is Bystolic different from other beta-blockers?

Nebivolol is highly selective for beta-1 heart receptors and uniquely stimulates nitric oxide production, causing blood vessel relaxation — a vasodilating effect that most other beta-blockers don't provide.

How long before Bystolic lowers my blood pressure?

Blood pressure reduction typically begins within the first week. Full effect at a given dose may take 2–4 weeks. Your clinician may adjust the dose gradually to achieve your blood pressure target.

Can I stop Bystolic suddenly?

No. Stopping beta-blockers abruptly — particularly in people with heart disease — can cause rebound tachycardia and potentially dangerous cardiac events. Always taper gradually under your clinician's supervision.

What side effects might I experience?

Fatigue, dizziness, slow heart rate, headache, and cold hands or feet are most common. Bystolic's high beta-1 selectivity makes it less likely to cause bronchospasm than non-selective beta-blockers — an advantage for people with mild respiratory conditions.

Is Bystolic safe for people with diabetes?

Beta-blockers can mask some hypoglycemia symptoms like rapid heartbeat. Bystolic's beta-1 selectivity minimizes this concern compared to non-selective agents, but people with diabetes should be aware and monitor blood sugar carefully.
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