Natroba

Brand for spinosad

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Most insurance accepted

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Available nationwide

What is Natroba?

Natroba is a prescription topical suspension used to treat head lice infestations in patients 6 months of age and older. It contains Natroba, a naturally derived insecticide produced by a soil bacterium, that kills lice through a mechanism distinct from older pediculicides. A key advantage is that a single 10-minute application is typically sufficient to treat an infestation—and nit combing is not required after treatment, which is a significant practical benefit. It's applied to dry hair and scalp, left on for 10 minutes, then rinsed off. A second treatment may be needed if live lice are seen 7 days after the first.

Neuronal excitation and louse death

Natroba activates nicotinic acetylcholine receptors in lice neurons in a unique way, causing continuous nerve firing, paralysis, and death of both adult lice and nymphs without significant human toxicity.

Ovicidal activity

Unlike some older lice treatments that kill only adult lice and require repeat applications to catch newly hatched nymphs, Natroba also kills lice eggs—often allowing a single treatment to clear the infestation completely.

No-nit-comb convenience

Because Natroba kills eggs as well as live lice, manual nit removal is not required after treatment—a significant practical advantage over pyrethrin and permethrin-based treatments that require time-consuming nit combing.

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Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

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