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Natroba (spinosad)
Virtual visit

Natroba (spinosad)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Natroba (spinosad) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Natroba (spinosad)?

Natroba is a prescription topical suspension used to treat head lice infestations in patients 6 months of age and older. It contains spinosad, a naturally derived insecticide produced by a soil bacterium, that kills lice through a mechanism distinct from older pediculicides. A key advantage is that a single 10-minute application is typically sufficient to treat an infestation—and nit combing is not required after treatment, which is a significant practical benefit. It's applied to dry hair and scalp, left on for 10 minutes, then rinsed off. A second treatment may be needed if live lice are seen 7 days after the first.

Neuronal excitation and louse death

Spinosad activates nicotinic acetylcholine receptors in lice neurons in a unique way, causing continuous nerve firing, paralysis, and death of both adult lice and nymphs without significant human toxicity.

Ovicidal activity

Unlike some older lice treatments that kill only adult lice and require repeat applications to catch newly hatched nymphs, Spinosad also kills lice eggs—often allowing a single treatment to clear the infestation completely.

No-nit-comb convenience

Because Spinosad kills eggs as well as live lice, manual nit removal is not required after treatment—a significant practical advantage over pyrethrin and permethrin-based treatments that require time-consuming nit combing.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

Is one treatment of Natroba usually enough for head lice?

Yes — a single 10-minute application clears lice infestations in most people. A second treatment 7 days later may be needed only if live lice are still visible after the first application.

Does Natroba kill lice eggs as well as adult lice?

Yes. Unlike some older lice treatments that only kill adult lice and require repeat applications to catch newly hatching nymphs, Natroba is ovicidal — killing both live lice and their eggs in a single application.

Do I need to do nit combing after using Natroba?

No. Because Natroba kills eggs as well as live lice, time-consuming nit combing is not required after treatment — a significant practical advantage over pediculicides that are not ovicidal.

What side effects might I experience?

Application site redness, irritation, and eye redness if the product contacts the eyes are the most commonly reported effects. Keep Natroba away from the eyes — rinse thoroughly with water if contact occurs.

Should household contacts be treated as well?

Household members and close contacts should be checked for lice and treated if live lice are found. Treating only confirmed cases rather than prophylactically treating everyone is the generally recommended approach.
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