General MedicineGeneral Medicine
Naltrexone

Naltrexone

Without insurance

With insurance

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Naltrexone?

Naltrexone is a non-addictive prescription medication used to support recovery from alcohol or opioid use disorder. Unlike medications that replace one substance with another, naltrexone works by blocking opioid receptors in the brain — the same receptors responsible for the pleasurable and reinforcing effects of alcohol and opioids. Taken daily as a pill or monthly as an injection, it reduces cravings over time and helps break the cycle of use. It works best as part of a broader recovery plan.

Opioid receptor blockade

Naltrexone binds to opioid receptors without activating them, preventing alcohol and opioids from producing their usual rewarding effects.

Craving reduction

By disrupting the brain's reward response, naltrexone gradually reduces the intensity and frequency of urges over time.

Non-habit-forming

Unlike some recovery medications, naltrexone carries no risk of dependence and does not produce a high at any dose.

Virtual visit with clinician

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

Thousands of customers trust us

“I feel like I'm finally on the right path to improving my health with the right support now! It's so refreshing and reassuring.”

—Emerald, Texas

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

—Kaylee, Louisiana

“I couldn't be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

—Nika, Tennessee

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