General
Naltrexone
Virtual visit

Naltrexone

Naltrexone is a prescription medication used to help reduce cravings and support recovery from alcohol or opioid use. At lower doses, it is also used to help manage chronic pain, fibromyalgia, and inflammation-related conditions. Whether you need a first-time prescription or a refill, our licensed providers can help you find the right form and dose through a quick virtual visit.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Naltrexone?

Naltrexone is a non-addictive prescription medication used to support recovery from alcohol or opioid use disorder. Unlike medications that replace one substance with another, naltrexone works by blocking opioid receptors in the brain — the same receptors responsible for the pleasurable and reinforcing effects of alcohol and opioids. Taken daily as a pill or monthly as an injection, it reduces cravings over time and helps break the cycle of use. It works best as part of a broader recovery plan.

Opioid receptor blockade

Naltrexone binds to opioid receptors without activating them, preventing alcohol and opioids from producing their usual rewarding effects.

Craving reduction

By disrupting the brain's reward response, naltrexone gradually reduces the intensity and frequency of urges over time.

Non-habit-forming

Unlike some recovery medications, naltrexone carries no risk of dependence and does not produce a high at any dose.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

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“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

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Get the care you need, without the wait.

Frequently Asked Questions

Is naltrexone addictive or habit-forming?

No. Naltrexone is not a controlled substance, does not produce a high at any dose, and carries no risk of dependence or addiction. It is safe for long-term use as part of a recovery program.

Can I take naltrexone while still using opioids?

No — you must be fully opioid-free for at least 7–10 days before starting naltrexone. Taking it while opioids are in your system will trigger sudden, severe withdrawal. Your clinician will verify opioid-free status before prescribing.

What happens if I take opioids while on naltrexone?

Naltrexone blocks opioid receptors, so opioids will have significantly reduced or no effect. Attempting to overcome this blockade with higher doses is extremely dangerous and can be fatal.

What side effects might I experience?

Nausea, stomach cramps, headache, fatigue, and sleep disturbances are most commonly reported — particularly when starting. These often improve within the first 1–2 weeks. Taking it with food reduces nausea.

What's the difference between naltrexone pills and the monthly injection (Vivitrol)?

Oral naltrexone is taken daily and requires consistent adherence. Vivitrol is a monthly extended-release injection that removes the daily pill burden — which can be a meaningful advantage for long-term recovery adherence.
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