General
Metformin HCl

Metformin HCl

Without insurance

With insurance

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Metformin HCl?

Metformin HCl is one of the most widely prescribed medications in the world, used as a first-line treatment for Type 2 diabetes. It works primarily by reducing the amount of glucose the liver releases into the bloodstream and by making cells more responsive to insulin—without stimulating the pancreas to produce more insulin. This means it lowers blood sugar effectively without the risk of hypoglycemia (dangerously low blood sugar) that comes with some other diabetes medications. It's taken once or twice daily with meals and has been used safely for decades.

Hepatic glucose reduction

Suppresses the liver's excessive release of stored glucose into the bloodstream—a major driver of elevated fasting blood sugar in Type 2 diabetes—without shutting down glucose production entirely.

Insulin sensitization

Improves how effectively muscle and fat cells respond to insulin, allowing them to absorb glucose from the bloodstream more efficiently and reducing the burden on the pancreas.

Weight-neutral to weight-friendly

Unlike many diabetes medications, Metformin HCl doesn't cause weight gain and may modestly support weight loss in some patients—an important advantage given the relationship between weight and blood sugar control.

Virtual visit with clinician

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

Thousands of customers trust us

“I feel like I'm finally on the right path to improving my health with the right support now! It's so refreshing and reassuring.”

—Emerald, Texas

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

—Kaylee, Louisiana

“I couldn't be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

—Nika, Tennessee

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