General
Megace (Megestrol)
Virtual visit

Megace (Megestrol)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Megace (Megestrol) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Megace (Megestrol)?

Megace is a synthetic progestin used primarily to stimulate appetite and promote weight gain in patients experiencing significant weight loss and anorexia associated with cancer, HIV/AIDS, or other serious illnesses. At the doses used for appetite stimulation, it works through hormonal and metabolic pathways that increase hunger and improve caloric intake. It's also used in some cases to treat certain hormone-sensitive breast and endometrial cancers. Available in tablet and oral suspension form, it's taken once or multiple times daily depending on the indication.

Appetite stimulation

At higher doses, Megestrol activates appetite-regulating pathways in the hypothalamus and may suppress pro-inflammatory cytokines like TNF-alpha and IL-6 that contribute to the anorexia and metabolic wasting seen in serious illness.

Weight and lean mass support

Promotes caloric intake and helps reverse unintentional weight loss in patients with cancer- or HIV-related cachexia—improving nutritional status, energy levels, and overall quality of life.

Hormonal anti-tumor activity

As a progestin, Megestrol can inhibit the growth of hormone receptor-positive breast and endometrial cancers by opposing estrogen's stimulating effects on tumor cell proliferation.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

How quickly does Megace improve appetite?

Many patients notice increased appetite within the first 2–4 weeks of starting Megace. Weight stabilization or gain may take longer, typically 4–8 weeks of consistent daily use.

Is Megace a steroid?

Megace is a synthetic progestin — related to the hormone progesterone — not a traditional anabolic or corticosteroid. However, at higher doses used for appetite stimulation, it can have some glucocorticoid-like effects.

Can Megace be used for cancer treatment as well as appetite?

Yes. At standard doses it's used for appetite stimulation and weight management in serious illness. It's also used at different doses to treat hormone receptor-positive breast and endometrial cancers.

What side effects might I experience?

Fluid retention, blood clot risk (DVT and PE), adrenal suppression with long-term use, and blood sugar elevation are the most significant concerns. These risks increase with dose and duration of use.

Does Megace interact with other medications?

Yes. Megace can interact with blood thinners, insulin, and other medications. Your clinician will review your full medication list and monitor for relevant interactions during treatment.
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