Medroxyprogesterone

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What is Medroxyprogesterone?

Medroxyprogesterone is a long-acting injectable contraceptive, given as a shot every three months to prevent pregnancy. It's one of the most effective forms of birth control available—more than 99% effective with perfect use—and requires no daily action from the patient. It works primarily by preventing ovulation, and secondarily by thickening cervical mucus to block sperm. Many users experience lighter periods or no periods at all, which some find a significant benefit. Fertility may take several months to return after stopping injections.

Ovulation suppression

High-dose progestin prevents the LH surge required for ovulation, consistently eliminating the possibility of egg release and fertilization throughout the 3-month injection period.

Cervical mucus thickening

Creates a dense cervical mucus barrier that significantly impedes sperm motility and penetration—providing a secondary layer of contraceptive protection even in the rare event ovulation occurs.

Menstrual changes

Many users experience significantly lighter periods, irregular spotting, or complete cessation of menstruation over time—a common and for many patients welcome side effect of continuous progestin exposure.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

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