Xiidra

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Most insurance accepted

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Available nationwide

What is Xiidra?

Xiidra is a prescription eye drop used to treat the signs and symptoms of dry eye disease, specifically targeting the underlying inflammatory process rather than simply lubricating the eye surface. It works by blocking LFA-1, a protein on the surface of immune cells that promotes inflammation in the tear glands and eye surface. By interrupting this inflammatory signaling, Xiidra reduces the immune-driven damage that disrupts tear production and eye surface health. It's applied twice daily and may take up to 12 weeks to produce the full benefit.

LFA-1 integrin blockade

Blocks the interaction between LFA-1 on T-lymphocytes and ICAM-1 on eye surface cells, preventing the immune cell activation and inflammatory cascade that damages the ocular surface and reduces tear production in dry eye disease.

Root-cause anti-inflammatory treatment

Rather than masking symptoms with artificial lubrication, Xiidra addresses the underlying inflammatory mechanism driving dry eye—improving both the symptoms patients feel and the clinical signs providers measure.

Dual symptom and sign improvement

Clinical trials demonstrated improvement in both patient-reported eye dryness and discomfort and objective measures of ocular surface damage—distinguishing it from lubricating drops that only relieve symptoms temporarily.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

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