General MedicineGeneral Medicine
Jublia

Jublia

Without insurance

With insurance

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Jublia?

Jublia is a prescription topical antifungal solution used to treat onychomycosis—fungal infections of the toenails. It's applied directly to the affected nail and surrounding skin once daily using a flow-through brush applicator that helps the medication penetrate the nail plate. Jublia works by blocking a key enzyme in the fungal cell membrane synthesis pathway, disrupting the fungus's ability to survive and spread. Treatment requires patience—because nails grow slowly, a full course takes 48 weeks, with clear nail growth becoming visible gradually over time.

Ergosterol synthesis inhibition

Blocks the fungal enzyme CYP51 (lanosterol 14α-demethylase), disrupting ergosterol production—a critical component of the fungal cell membrane—causing membrane instability and fungal cell death.

High nail penetration

Jublia's unique chemical properties allow it to penetrate the nail plate and reach the nail bed where the infection resides more effectively than older topical antifungals, improving clinical outcomes.

48-week topical course

Requires daily application for approximately one year to match the slow growth rate of toenails—consistent application throughout the full course is essential for clearing the infection completely.

Virtual visit with clinician

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

Thousands of customers trust us

“I feel like I'm finally on the right path to improving my health with the right support now! It's so refreshing and reassuring.”

—Emerald, Texas

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

—Kaylee, Louisiana

“I couldn't be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

—Nika, Tennessee

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