General MedicineGeneral Medicine
Fluvoxamine

Fluvoxamine

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Most insurance accepted

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Available nationwide

What is Fluvoxamine?

Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI) with FDA approval specifically for obsessive-compulsive disorder (OCD) in adults and children. While other SSRIs are also used for OCD off-label, Fluvoxamine is one of the few with a primary OCD indication. It works by blocking serotonin reuptake, increasing serotonin availability in the brain—which is believed to reduce the intensity of obsessive thoughts and compulsive behaviors over time. It also has sigma-1 receptor activity, which may contribute to additional neurological effects. It's taken once daily or in divided doses depending on the total dose prescribed.

Serotonin reuptake inhibition

Blocks the serotonin transporter, increasing serotonergic neurotransmission in brain circuits—including the orbitofrontal-striatal pathways—implicated in the obsessive thought cycles and compulsive behavioral loops of OCD.

Primary OCD indication

Unlike most SSRIs that are approved for depression as their primary indication with OCD as a secondary use, Fluvoxamine was developed and approved specifically for OCD—with a clinical trial database focused on obsessive-compulsive symptom reduction.

Sigma-1 receptor activity

Fluvoxamine has notable affinity for sigma-1 receptors—a pharmacological property not shared by other SSRIs—which may contribute to its efficacy profile and has generated research interest in additional neurological and inflammatory applications.

Virtual visit with clinician

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

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