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Fluticasone/Salmeterol (Advair)
Virtual visit

Fluticasone/Salmeterol (Advair)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Fluticasone/Salmeterol (Advair) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Advair (Fluticasone/Salmeterol)?

Advair is a combination inhaler containing fluticasone, an inhaled corticosteroid, and salmeterol, a long-acting beta-2 agonist bronchodilator. Together, they provide both anti-inflammatory control and sustained airway opening for people with asthma or COPD. Fluticasone reduces chronic airway inflammation that makes the lungs hypersensitive, while salmeterol relaxes the muscles surrounding the airways to keep them open for up to 12 hours. It's used as a maintenance medication taken twice daily—not a rescue inhaler—and works best when used consistently as part of a long-term management plan.

Dual maintenance mechanism

Fluticasone reduces the chronic airway inflammation that underlies asthma and COPD, while salmeterol provides sustained 12-hour bronchodilation—together addressing both the inflammatory root cause and the resulting airway constriction.

Long-acting bronchodilation

Salmeterol's extended duration means a single morning and evening dose provides continuous airway muscle relaxation throughout the day and night, reducing symptoms and improving exercise tolerance.

Reduced exacerbation frequency

Consistent use of the combined steroid and long-acting bronchodilator significantly lowers the frequency of asthma and COPD flare-ups and reduces dependence on short-acting rescue inhalers.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

Can I use Advair as a rescue inhaler during an attack?

No. Advair is a maintenance inhaler — used daily to prevent symptoms, not to treat acute attacks. A separate short-acting rescue inhaler like albuterol should always be kept on hand for sudden symptoms.

How long before Advair improves my asthma or COPD?

Salmeterol's bronchodilating effect works within minutes, but the full anti-inflammatory benefit of fluticasone builds over days to weeks of consistent twice-daily use. Daily use — even on good days — is essential.

Do I need to rinse my mouth after using Advair?

Yes. Rinsing with water and spitting after each use reduces the risk of oral thrush — a fungal infection that can develop when inhaled steroid deposits in the mouth and throat.

What side effects might I experience?

Oral thrush, hoarseness, throat irritation, and headache are most common. Rinsing after use significantly reduces thrush risk. Long-acting beta-agonists like salmeterol should not be used without an ICS — Advair provides both together.

Is there a generic version of Advair?

Yes — fluticasone/salmeterol inhalers are available as generics and may be significantly less expensive. Ask your clinician or pharmacist whether a generic formulation is appropriate for your device and technique.
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