General
Fluoxetine (Prozac)
Virtual visit

Fluoxetine (Prozac)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Fluoxetine (Prozac) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Fluoxetine (Prozac)?

Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) and one of the most widely recognized antidepressants in the world. It's approved for major depressive disorder, OCD, bulimia nervosa, panic disorder, bipolar depression (in combination), and premenstrual dysphoric disorder. Fluoxetine has the longest half-life of any SSRI—5–6 days—which makes it the most forgiving if a dose is missed and allows for easier discontinuation without the withdrawal symptoms that can accompany shorter-acting SSRIs. It's taken once daily, often in the morning due to its mildly activating nature.

Serotonin reuptake inhibition

Blocks the serotonin transporter, increasing serotonin availability in the synaptic space to regulate mood, reduce anxiety, and improve emotional stability across depression, OCD, and related conditions.

Longest SSRI half-life

With a half-life of 5–6 days (and an active metabolite lasting even longer), Fluoxetine is uniquely forgiving of missed doses and produces minimal discontinuation symptoms—an important practical advantage for patients who struggle with consistent adherence.

Multi-condition approval

One of the few SSRIs approved for bulimia nervosa, with evidence for reducing binge-purge episodes alongside its established efficacy for depression, OCD, panic disorder, and PMDD—offering broad coverage across comorbid psychiatric presentations.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

What conditions is Prozac approved for?

Prozac is FDA-approved for major depression, OCD, bulimia nervosa, panic disorder, bipolar depression (in combination with olanzapine), and PMDD — one of the broadest indication lists among SSRIs.

How is Prozac different from other SSRIs?

Prozac has the longest half-life of any SSRI — 5–6 days, with an active metabolite lasting even longer. This makes it the most forgiving of missed doses and the easiest to discontinue without significant withdrawal symptoms.

How long before Prozac starts working?

Most people begin noticing mood improvements within 2–4 weeks. Full antidepressant benefit typically takes 4–6 weeks. Because of its long half-life, it continues working for days even if a dose is missed.

What side effects might I experience?

Nausea, insomnia, headache, dry mouth, and sexual side effects are most common. Prozac's activating properties — more energizing than sedating — can worsen insomnia in some patients, which is why morning dosing is often recommended.

Is Prozac safe during pregnancy?

Prozac is one of the more studied SSRIs in pregnancy. The decision to continue, switch, or stop requires careful risk-benefit discussion — untreated depression during pregnancy also carries risks that must be weighed.
Logo

© 2026 Path Healthcare Systems Corp.