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Eucrisa (crisaborole)
Virtual visit

Eucrisa (crisaborole)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Eucrisa (crisaborole) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Eucrisa (crisaborole)?

Eucrisa is a prescription non-steroidal topical ointment approved to treat mild to moderate atopic dermatitis (eczema) in patients aged 3 months and older. It works by inhibiting PDE4—an enzyme that drives the inflammatory cycle in eczema—reducing the skin inflammation, itching, and redness of flares without the side effects associated with topical corticosteroids. It's applied twice daily to affected areas and offers a steroid-free alternative for patients who need ongoing eczema management, are concerned about steroid side effects, or are treating sensitive skin areas.

PDE4 inhibition

Blocks phosphodiesterase-4, an enzyme that breaks down cyclic AMP—raising cAMP levels in immune cells and dampening the production of pro-inflammatory cytokines that drive the itch-scratch cycle of atopic dermatitis.

Steroid-free mechanism

Provides meaningful eczema control through an anti-inflammatory pathway completely distinct from corticosteroids—offering an option free from the skin thinning, pigmentation changes, and HPA axis concerns associated with long-term topical steroid use.

Broad age approval

Approved for use in patients as young as 3 months, making it one of the few non-steroidal prescription options available for infants and young children with eczema—an age group where steroid use requires particular caution.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.

Emerald

My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.

Kaylee

I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.

Nika

Get the care you need, without the wait.

Frequently Asked Questions

What age can Eucrisa be used for?

Eucrisa is approved for patients as young as 3 months old — making it one of the few non-steroidal prescription eczema treatments available for infants, where topical steroid use requires extra caution.

How quickly does Eucrisa work for eczema?

Improvement in itch and inflammation is typically noticed within 2–4 weeks of twice-daily use. Visible skin clearing develops over 4–8 weeks of consistent treatment.

Can Eucrisa be used on any part of the body?

Eucrisa can be applied to affected areas anywhere on the body — including the face, which is more sensitive and where topical steroids carry greater risk. Avoid contact with eyes and mucous membranes.

What side effects might I experience?

Burning or stinging at the application site immediately after applying is the most commonly reported effect — particularly in the first few applications. This usually decreases as treatment continues and skin begins to heal.

Is Eucrisa a steroid?

No. Eucrisa is a PDE4 inhibitor — a completely different mechanism from corticosteroids. It can be used on sensitive areas without the skin-thinning or pigmentation changes associated with long-term topical steroid use.
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