General
Ethinyl Estradiol/Norethindrone (Lo Loestrin Fe)
Virtual visit

Ethinyl Estradiol/Norethindrone (Lo Loestrin Fe)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Ethinyl Estradiol/Norethindrone (Lo Loestrin Fe) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Lo Loestrin Fe?

Lo Loestrin Fe is a low-dose combination oral contraceptive containing estrogen and progestin, along with a small amount of iron. It contains one of the lowest estrogen doses available in a combined pill, which may reduce estrogen-related side effects while still providing highly effective pregnancy prevention. The iron tablets included in the pack help replenish iron levels during the days of your period. Taken daily as directed, it works through three complementary hormonal mechanisms to prevent pregnancy reliably when used consistently.

Ovulation suppression

The estrogen and progestin combination prevents the hormonal surge needed to release an egg, eliminating the possibility of fertilization during the cycle.

Cervical mucus thickening

Progestin thickens cervical mucus, creating a barrier that makes it significantly harder for sperm to reach and fertilize an egg even if ovulation were to occur.

Uterine lining changes

Alters the endometrial lining to make implantation less likely as an additional layer of contraceptive protection—while the low estrogen dose helps minimize bloating, breast tenderness, and other hormone-related side effects.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

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What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

What makes Lo Loestrin Fe different from other birth control pills?

Lo Loestrin Fe contains one of the lowest estrogen doses available in a combined pill — 10 mcg of ethinyl estradiol — which may reduce estrogen-related side effects like breast tenderness and nausea.

What are the iron tablets for?

The 4 inactive pills in the pack contain ferrous fumarate (iron) to help replenish iron levels during your period. Taking them consistently maintains the daily habit even during the hormone-free interval.

What happens if I miss a pill?

A missed pill increases the risk of pregnancy. Follow the package instructions or your clinician's guidance on what to do — backup contraception may be needed depending on when in the pack the dose was missed.

What side effects might I experience?

Irregular bleeding or spotting is the most commonly reported side effect, particularly in the first few months. Headache, nausea, and mood changes can also occur. Most side effects improve after 2–3 months.

Does Lo Loestrin Fe protect against sexually transmitted infections?

No. Like all hormonal contraceptives, Lo Loestrin Fe does not protect against STIs. Condoms should be used if STI prevention is also needed alongside contraception.
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