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Emgality (Galcanezumab)
Virtual visit

Emgality (Galcanezumab)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Emgality (Galcanezumab) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Emgality (Galcanezumab)?

Emgality is a CGRP monoclonal antibody injection used for the preventive treatment of migraine in adults and for the treatment of episodic cluster headache. It works by binding to and blocking calcitonin gene-related peptide (CGRP), a neuropeptide that is central to the initiation of migraine and cluster headache attacks. By neutralizing CGRP before it can trigger pain signaling, Emgality reduces both the frequency and severity of attacks over time. For migraine prevention, it's injected once monthly; for cluster headache, a higher loading dose is given at the start of a cluster period.

CGRP ligand neutralization

Binds directly to the CGRP molecule—rather than its receptor—preventing it from triggering the trigeminal inflammatory cascade that initiates migraine and cluster headache pain.

Migraine and cluster headache coverage

One of the few treatments approved for both episodic migraine prevention and episodic cluster headache—a severe, poorly-treated headache disorder where treatment options have historically been very limited.

Once-monthly preventive dosing

A single monthly subcutaneous injection provides continuous CGRP neutralization and sustained reduction in attack frequency—significantly simpler than daily oral preventive medications and with effects maintained as long as treatment continues.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

How is Emgality different from triptans?

Emgality prevents migraines from occurring — it's not used to stop an attack in progress. Triptans are taken acutely during an attack. They serve completely different roles and can be used together in a comprehensive migraine plan.

How quickly does Emgality reduce migraine frequency?

Many people notice a reduction in migraine days within the first month of treatment. Clinical trials showed continued improvement over 3–6 months of consistent monthly dosing.

Is Emgality also approved for cluster headaches?

Yes. Emgality is FDA-approved for both episodic migraine prevention and episodic cluster headache — one of the few preventive treatments approved for cluster headache, which is notoriously difficult to treat.

What side effects might I experience?

Injection site reactions — pain, redness, and bruising — are the most commonly reported effects. Constipation has been reported in a subset of patients. Serious systemic side effects are uncommon given the targeted mechanism.

How long do I need to stay on Emgality to benefit?

Preventive benefit builds over the first 3–6 months. Most clinicians reassess response after 3–6 months to determine whether continued treatment is appropriate and whether the frequency of migraines has meaningfully decreased.
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