Duloxetine

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Available nationwide

What is Duloxetine?

Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) prescribed for depression, anxiety, chronic pain conditions like fibromyalgia, and nerve pain associated with diabetes. By increasing the availability of two key neurotransmitters—serotonin and norepinephrine—it helps regulate mood, reduce emotional distress, and dampen pain signals in the nervous system. Taken once daily, it typically takes 2–4 weeks before mood improvements are noticed, while pain relief may develop more gradually over several weeks.

Dual neurotransmitter action

Blocks the reabsorption of both serotonin and norepinephrine in the brain, increasing their availability to stabilize mood and reduce anxiety more broadly than SSRIs alone.

Central pain modulation

Norepinephrine plays a key role in how the brain processes pain signals—Duloxetine helps turn down that volume, making it effective for chronic nerve and musculoskeletal pain.

Whole-body benefit

A single medication can simultaneously address depression or anxiety and physical pain symptoms, which often co-occur and reinforce each other in many patients.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

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