General
Diamox (acetazolamide)
Virtual visit

Diamox (acetazolamide)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Diamox (acetazolamide) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Diamox (acetazolamide)?

Diamox is a carbonic anhydrase inhibitor primarily used to prevent and treat altitude sickness, reduce intraocular pressure in glaucoma, and manage certain types of seizures and fluid retention. It works by blocking an enzyme involved in fluid and acid-base balance throughout the body—in the kidneys, eyes, and brain. For altitude sickness, it accelerates the body's acclimatization process by altering the breathing drive and blood chemistry. It's taken orally, with dosing depending significantly on which condition is being treated.

Carbonic anhydrase inhibition

Blocks the carbonic anhydrase enzyme, altering bicarbonate handling in the kidneys and other tissues—producing effects on fluid balance, intraocular pressure, and respiratory drive depending on where it acts.

Altitude acclimatization

Stimulates faster and deeper breathing by creating a mild metabolic acidosis, helping the body adjust to lower oxygen levels at high altitude more quickly and reducing the headache, nausea, and fatigue of acute mountain sickness.

Intraocular pressure reduction

Decreases production of aqueous humor in the eye, lowering pressure inside the eye—making it a useful option for managing glaucoma, particularly when eye drops alone aren't sufficient.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

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Frequently Asked Questions

How far in advance should I start Diamox for altitude sickness?

For altitude sickness prevention, most clinicians recommend starting Diamox 1–2 days before ascending. This gives the medication time to begin accelerating your body's acclimatization process before exposure to high altitude.

Will Diamox completely prevent altitude sickness?

It significantly reduces the risk and severity of altitude sickness but doesn't guarantee complete prevention. Other precautions — ascending gradually, staying hydrated, and descending if symptoms worsen — are still essential.

Why does Diamox make me urinate more frequently?

Diamox is a carbonic anhydrase inhibitor that also has a mild diuretic effect. Increased urination is expected and helps drive the mild metabolic acidosis that stimulates deeper breathing at altitude.

What side effects might I experience?

Tingling in the hands, feet, and face is the most distinctive and common side effect. Increased urination, altered taste of carbonated beverages, and drowsiness can also occur. These typically resolve when the medication is stopped.

Can I take Diamox if I'm allergic to sulfa drugs?

Use caution. Diamox contains a sulfonamide group and may cross-react in people with sulfa allergies. Inform your clinician of any sulfa allergy before taking it — alternatives may be recommended.
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