General
Cortisone
Virtual visit

Cortisone

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Cortisone or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Cortisone?

Cortisone is a corticosteroid used to reduce inflammation and suppress immune system overactivity in a wide range of conditions—including arthritis, allergic reactions, skin conditions, and autoimmune disorders. It's a prodrug that the body converts to cortisol, the active form. Cortisone can be taken orally, but is most commonly administered as an injection directly into a joint, tendon, or soft tissue for targeted, localized anti-inflammatory relief. Injected cortisone typically provides relief within a few days and can last weeks to months depending on the condition and location treated.

Prodrug corticosteroid conversion

Cortisone is converted to cortisol in the liver, which then suppresses the production of prostaglandins, cytokines, and other inflammatory mediators—reducing swelling, pain, and immune-driven tissue damage at the site of inflammation.

Targeted joint injection benefit

When injected directly into an inflamed joint or bursa, cortisone delivers high local concentrations of anti-inflammatory steroid exactly where it's needed—minimizing systemic exposure while maximizing relief at the treatment site.

Broad multi-condition application

Used across arthritis, bursitis, tendinitis, allergic reactions, and autoimmune flares—offering fast, potent anti-inflammatory relief for both acute and chronic inflammatory conditions.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

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What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

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Get the care you need, without the wait.

Frequently Asked Questions

What is cortisone most commonly used for?

Cortisone is most often given as a targeted injection into an inflamed joint, tendon, or bursa to reduce localized pain and swelling. It's also available orally for broader inflammatory conditions requiring systemic treatment.

How long does a cortisone injection last?

Relief from a cortisone injection typically begins within 1–3 days and can last anywhere from several weeks to several months — depending on the condition, the joint, and how your body responds.

How many cortisone injections can I get in one joint?

Most clinicians recommend limiting injections to 3–4 per year in any single joint. Frequent injections can weaken surrounding tissue and cartilage over time — spacing them appropriately helps minimize this risk.

What side effects might I experience?

A temporary flare of pain for 24–48 hours after injection is common before relief sets in. Localized skin thinning, lightening of skin color near the injection site, and elevated blood sugar can occur — particularly in people with diabetes.

Can oral cortisone be taken long-term?

Long-term oral corticosteroid use carries significant risks including bone density loss, immune suppression, weight gain, and adrenal suppression. It is generally used for the shortest duration possible and tapered carefully.
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