Chlorhexidine

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What is Chlorhexidine?

Chlorhexidine is a prescription antiseptic oral rinse used to treat gingivitis—inflammation of the gums caused by bacterial plaque. It's typically prescribed following dental procedures or for patients with significant gum disease to reduce the bacterial load in the mouth and allow gum tissue to heal. Chlorhexidine works by disrupting bacterial cell membranes, killing the bacteria responsible for plaque and gum inflammation. It's used twice daily as a rinse for 30 seconds—not swallowed—and may cause temporary tooth staining and altered taste with extended use.

Bacterial membrane disruption

Chlorhexidine binds to negatively charged bacterial cell walls and membranes, disrupting their integrity and causing bacterial cell death—reducing the plaque-forming bacteria responsible for gingivitis.

Substantivity advantage

Chlorhexidine adheres to oral tissues and continues releasing antibacterial activity for hours after rinsing—a property called substantivity—providing longer-lasting bacterial suppression than standard antiseptic rinses.

Post-procedural gum healing

By significantly reducing oral bacterial burden, Chlorhexidine creates a cleaner environment for gum tissue to heal after dental procedures or during treatment of periodontitis—complementing mechanical cleaning and professional dental care.

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