General
Celiac Disease Panel
Lab test

Celiac Disease Panel

Ordered for people with GI symptoms, unexplained fatigue, nutrient deficiencies, or a family history of celiac disease who want to screen for a gluten-related autoimmune condition. Must be consuming a normal gluten-containing diet for at least 6 weeks before testing. Results reviewed by a General Medicine clinician.

Receive actionable insights and deep analysis—not just lab values– in as little as 48 hours

Clear guidance, and follow-up care available

Simple, online scheduling for labs and everything else

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is a Celiac Disease Panel?

The Celiac Disease Panel measures three antibodies that together provide the most comprehensive blood-based screen for celiac disease — the autoimmune condition triggered by gluten that damages the small intestine. Each antibody adds a different layer of sensitivity or specificity, giving a more complete and accurate picture than any single marker alone.

Tissue transglutaminase (tTG) antibodies

The primary and most sensitive marker for celiac disease — tTG IgA antibodies reflect the immune reaction to gluten that causes intestinal damage, and are the first-line test in most celiac screening protocols.

Deamidated gliadin peptide (DGP) antibodies

Provide additional sensitivity and specificity, particularly for detecting celiac disease in people with IgA deficiency where tTG-IgA testing may produce false negatives.

Endomysial antibody

A highly specific confirmatory marker — a positive endomysial antibody result is among the strongest blood-based indicators of celiac disease and helps confirm findings when other markers are borderline.

Complete insights in as little as 48 hours

1

Book your test

Instantly schedule at 2,000+ labs nationwide, at a time that works for you. Most visits take 15 minutes or less, with both walk-ins and appointments available.

2

Get results in 48 hours

Your results are delivered quickly—and reviewed by medical professionals. You’ll get clear explanations, robust health insights, and recommended next steps tailored to your health needs.

3

Take action with physician guidance

Choose to review your results and manage your plan with a General Medicine physician—or simply use the insights on your own.

4

Track progress over time

Repeat annually to see trends, improvements, and new emerging risks or book individual tests that focus on your set goals

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What's included

Test type

Blood sample

Collection method

Venipuncture

Fasting

Not required

Results processing time

1 to 4 days

tissue Transglutaminase (tTG) Antibodies

These antibodies help evaluate whether your immune system is reacting to gluten, a hallmark of celiac disease.

Deamidated Gliadin Peptide (DGP) Antibodies

These provide additional sensitivity and specificity for diagnosing or ruling out celiac disease.

Endomysial Antibody

A highly specific antibody used to confirm gluten-related autoimmune activity in celiac disease.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

What our customers have to say

Hear from people who felt heard, understood, and supported on General Medicine.

“I found the ease of setting the appointment and how quickly I was able to be seen to be amazing. The physician was very friendly and amazingly helpful.”

Natalie, Texas

“The chat visit was super convenient. The doctor was friendly and took the time needed to answer any questions I had. The prescription I needed was called in and ready the same afternoon.”

Dustin, Tennessee

“I loved my General Medicine experience. It gave me peace of mind to know someone cared and I felt they listened to what I was saying.”

Ann, Florida

“General Medicine is easily the most approachable, efficient, high-quality, and responsive care team I've had the pleasure of working with.”

John, Utah

“General Medicine helped me get the imaging and blood work I needed, referred me to the right specialists, and even helped me find a new family doctor.”

Bridget, Mississippi

Order your lab today.

Frequently asked questions

What does the Celiac Disease Panel test for?

The panel measures antibodies associated with celiac disease — most importantly tissue transglutaminase IgA (tTG-IgA) and total IgA (to confirm you can produce IgA antibodies). Some panels also include deamidated gliadin peptide antibodies (DGP). Elevated antibodies suggest an immune reaction to gluten consistent with celiac disease.

Do I need to be eating gluten for the test to be accurate?

Yes — this is critically important. If you have already eliminated or significantly reduced gluten, antibody levels will drop and the test may produce a false negative. You should be eating a normal gluten-containing diet (at least 1–2 servings daily) for at least 6 weeks before testing.

Can this test diagnose celiac disease on its own?

A positive panel is strong evidence, but definitive celiac diagnosis requires small intestinal biopsy (via endoscopy) to confirm villous atrophy. The blood panel is the appropriate first step and guides whether biopsy is needed.

What's the difference between celiac disease and gluten sensitivity?

Celiac disease is an autoimmune condition causing intestinal damage — detected by antibody testing and biopsy. Non-celiac gluten sensitivity causes similar symptoms but without immune damage or positive antibodies. The panel tests for celiac specifically; gluten sensitivity has no reliable blood test.

I have IgA deficiency — will this test work for me?

Total IgA is included in the panel to check for IgA deficiency. If your IgA is low, tTG-IgA results may be falsely negative — in that case, IgG-based antibody tests (DGP-IgG) are used instead. A clinician can ensure the right interpretation.
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