Cefaclor

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What is Cefaclor?

Cefaclor is a second-generation cephalosporin antibiotic used to treat bacterial infections of the respiratory tract, ears, skin, and urinary tract. It works by disrupting bacterial cell wall synthesis—binding to penicillin-binding proteins and preventing the cross-linking of the peptidoglycan structure that gives cell walls their strength, causing bacteria to lyse and die. As a second-generation cephalosporin, it has better gram-negative coverage than first-generation agents while retaining good gram-positive activity. It's available as capsules or a liquid suspension and is typically taken two to three times daily.

Beta-lactam cell wall disruption

Binds to penicillin-binding proteins in the bacterial cell wall, inhibiting the transpeptidation reaction needed to cross-link peptidoglycan—structurally weakening the wall and causing bacterial cell lysis and death.

Second-generation spectrum

Improved gram-negative coverage compared to first-generation cephalosporins, with activity against H. influenzae and Moraxella catarrhalis—pathogens commonly responsible for ear infections, sinusitis, and lower respiratory tract infections.

Pediatric-friendly suspension

Available as an oral suspension in addition to capsules, making Cefaclor practical for children with ear infections, respiratory infections, or skin infections who cannot swallow tablets.

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Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

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