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Cabtreo (Benzoyl peroxide - clindamycin - adapalene)
Virtual visit

Cabtreo (Benzoyl peroxide - clindamycin - adapalene)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Cabtreo (Benzoyl peroxide - clindamycin - adapalene) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Cabtreo?

Cabtreo is a prescription topical gel containing three acne-fighting ingredients in a single formulation: benzoyl peroxide, clindamycin, and adapalene. This triple combination addresses acne from three distinct angles—benzoyl peroxide and clindamycin attack the bacteria that trigger inflammatory breakouts, while adapalene normalizes the skin cell turnover that causes pores to clog. By targeting multiple pathways simultaneously in one product, Cabtreo simplifies the acne treatment regimen and delivers combination therapy that is more effective than any single or dual-ingredient treatment. Applied once daily, it's approved for patients 12 and older.

Triple-mechanism acne treatment

Adapalene normalizes follicular keratinization to prevent pore clogging, clindamycin suppresses C. acnes protein synthesis, and benzoyl peroxide kills bacteria through oxidative action—three independent pathways targeting acne simultaneously in one once-daily application.

Resistance prevention built in

Benzoyl peroxide's inclusion alongside the antibiotic clindamycin significantly reduces the risk of antibiotic resistance developing—a major advantage of multi-ingredient formulations over antibiotic-only treatments used long-term.

Simplified triple therapy

Combining three established acne treatments into a single gel eliminates the need to layer multiple products and coordinate timing of different formulations, improving patient adherence to a regimen that would otherwise require three separate applications.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

What makes Cabtreo different from other acne products?

Cabtreo is the only prescription topical gel containing all three key acne-fighting ingredients — a retinoid (adapalene), an antibiotic (clindamycin), and benzoyl peroxide — in a single once-daily application.

How long before Cabtreo clears my acne?

Clinical trials showed significant reduction in inflammatory and non-inflammatory lesions after 12 weeks. Results continue improving over 3–6 months of once-daily use — consistency is essential for full benefit.

Can Cabtreo bleach my clothes or bedding?

Yes. The benzoyl peroxide component is a bleaching agent that can stain or discolor fabric. Allow the gel to fully absorb before contact with clothing or bedding — using white pillowcases helps avoid visible staining.

What side effects might I experience?

Dryness, peeling, redness, and stinging — particularly in the first 2–4 weeks — are expected as adapalene increases cell turnover and benzoyl peroxide exerts its antibacterial and keratolytic action. A non-comedogenic moisturizer helps.

Should I apply Cabtreo to my entire face or just breakouts?

Apply a thin layer to the entire affected area — not just individual pimples. Treating the whole zone prevents new lesions from forming in adjacent areas and is clinically more effective than spot treatment.
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