General MedicineGeneral Medicine
Allopurinol

Allopurinol

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Most insurance accepted

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Available nationwide

What is Allopurinol?

Allopurinol is a prescription medication used for the long-term prevention of gout and to manage elevated uric acid in patients receiving chemotherapy. It works by blocking xanthine oxidase—the enzyme responsible for the final steps of uric acid production—reducing the body's overall uric acid output. Unlike medications that treat gout flares acutely, Allopurinol is taken daily as a preventive measure. It doesn't treat active attacks, and flares may temporarily increase when starting it as urate crystals begin to dissolve. It's one of the most widely used and cost-effective urate-lowering therapies available.

Xanthine oxidase inhibition

Blocks the enzyme that converts hypoxanthine and xanthine into uric acid, reducing uric acid production at its source—lowering serum urate levels below the crystallization threshold with consistent daily use.

Crystal dissolution over time

As serum uric acid levels fall and remain low, existing monosodium urate crystal deposits in joints and soft tissues gradually dissolve—reducing the frequency of gout flares and the risk of tophi formation over months to years.

Chemotherapy hyperuricemia prevention

Used alongside chemotherapy to prevent tumor lysis syndrome—the dangerous surge in uric acid that occurs when large numbers of cancer cells are rapidly killed and release their cellular contents into the bloodstream.

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Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

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