Imiquimod

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What is Imiquimod?

Imiquimod is a prescription topical cream used to treat external genital and perianal warts caused by HPV, actinic keratoses (precancerous skin lesions), and certain superficial basal cell carcinomas. Unlike treatments that physically destroy warts or lesions, imiquimod works by activating the body's own immune response at the application site—stimulating the skin's local defenses to recognize and attack abnormal tissue. It's applied directly to the affected area three times per week for up to 16 weeks depending on the condition, and is designed for patient self-administration at home.

Immune response modifier

Binds to toll-like receptor 7 (TLR7) on immune cells in the skin, triggering the innate immune system to produce interferon-alpha and other cytokines that activate local antiviral and antitumor immune responses.

HPV lesion clearance

By stimulating local immune activation, Imiquimod helps the immune system recognize and clear HPV-infected wart tissue—addressing the viral component of the infection rather than just physically removing the lesion.

Home-applied immunotherapy

Unlike office-based treatments such as cryotherapy or podophyllin, Imiquimod empowers patients to treat warts and actinic keratoses at home on a scheduled basis, providing a convenient alternative for appropriate lesions.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

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