General
Ajovy (Fremanezumab)
Virtual visit

Ajovy (Fremanezumab)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Ajovy (Fremanezumab) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

Visit options

Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Chat Visit

$30

w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Ajovy (Fremanezumab)?

Ajovy is a CGRP monoclonal antibody injection used for the preventive treatment of migraine in adults who experience either episodic or chronic migraines. It works by targeting calcitonin gene-related peptide (CGRP), a protein released during migraines that triggers the pain and inflammation of the attack. By neutralizing CGRP before it can bind to its receptors, Ajovy reduces both the frequency and severity of migraines over time. It can be injected once monthly or once quarterly depending on the dosing option chosen, making it one of the most flexible migraine preventives available.

CGRP neutralization

Binds directly to CGRP—the neuropeptide released during migraine attacks that causes vasodilation and neurogenic inflammation—preventing it from reaching its receptors and triggering the pain cascade.

Preventive monthly or quarterly dosing

Offers two dosing schedules—monthly injections or a higher quarterly dose—giving patients and providers flexibility to choose the frequency that best fits lifestyle and preference.

Episodic and chronic migraine coverage

Approved for both episodic (fewer than 15 headache days/month) and chronic migraine (15 or more), making it one of the few preventive treatments with evidence across both migraine classifications.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

Your care plan
Clinician

What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

Emerald

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

Kaylee

“I couldn’t be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

Nika

Get the care you need, without the wait.

Frequently Asked Questions

How is Ajovy different from triptans for migraines?

Ajovy prevents migraines from occurring — it's not used during an attack. Triptans are taken acutely to stop an attack in progress. They serve completely different roles in migraine management and can be used together.

Can I choose between monthly and quarterly dosing?

Yes. Ajovy offers both dosing options — one injection monthly or a higher dose once every 3 months. Your clinician will help you decide based on your preference and clinical considerations.

How long before Ajovy reduces my migraine frequency?

Many people notice a reduction in migraine days within the first month of treatment. Full benefit typically develops over 3–6 months of consistent use.

What side effects might I experience?

Injection site reactions — pain, redness, hardness, and bruising — are the most commonly reported effects. They are generally mild and transient. Systemic side effects are uncommon given the targeted mechanism.

Is Ajovy approved for both episodic and chronic migraine?

Yes. Ajovy is FDA-approved for prevention of both episodic migraine (fewer than 15 headache days/month) and chronic migraine (15 or more) — one of the broader approvals among CGRP-targeting migraine preventives.
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