General MedicineGeneral Medicine
Acyclovir

Acyclovir

Generic for Zovirax

Without insurance

With insurance

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is acyclovir?

Acyclovir is an antiviral medication used to treat infections caused by herpes simplex virus (HSV-1 and HSV-2) and varicella-zoster virus, including genital herpes, cold sores, chickenpox, and shingles. It works by targeting a viral enzyme to block DNA replication inside infected cells, limiting the virus's ability to spread and reproduce. Acyclovir is available in oral tablets, topical cream, and intravenous formulations. The oral form is used for initial and recurrent outbreaks and for suppressive therapy. The topical cream provides mild relief for cold sores, and IV acyclovir is used for severe or systemic herpes infections.

Viral thymidine kinase activation

Acyclovir is selectively activated by herpes virus-encoded thymidine kinase inside infected cells, concentrating its antiviral effect where the virus is actively replicating while minimizing effects on uninfected tissue.

DNA polymerase chain termination

The activated form of acyclovir is incorporated into viral DNA and acts as a chain terminator, halting the replication of viral genetic material and preventing the production of new infectious virus particles.

Multiple formulation versatility

Available as oral tablets for systemic treatment and suppression, topical cream for local cold sore relief, and IV formulation for severe or disseminated infections — providing treatment options across the full spectrum of herpes virus disease severity.

Virtual visit with clinician

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

5 out of 5 stars on Trustpilot

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

5 out of 5 stars on Trustpilot

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

5 out of 5 stars on Trustpilot

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

5 out of 5 stars on Trustpilot

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

5 out of 5 stars on Trustpilot

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

5 out of 5 stars on Trustpilot

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

5 out of 5 stars on Trustpilot

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