General
Abilify (Aripiprazole)
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Abilify (Aripiprazole)

With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Abilify (Aripiprazole) or a refill of an existing one.

Licensed providers in all 50 states

Expert-guided, evidence-based treatments

Skip the trip to the doctor's office

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Costs shown are for the visit only. You'll pay for medication at your preferred pharmacy.

Video Visit

$25

Est. or $100 w/o insurance

Most insurance accepted

Board-certified

No hidden fees

Available nationwide

What is Abilify (Aripiprazole)?

Abilify is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, major depressive disorder (as an add-on treatment), irritability associated with autism spectrum disorder, and Tourette's disorder. Unlike older antipsychotics that broadly block dopamine receptors, Aripiprazole acts as a partial agonist—meaning it both activates and moderates dopamine activity depending on whether levels are too high or too low. This nuanced mechanism is why it's often better tolerated than other antipsychotics, with less risk of weight gain, sedation, and metabolic effects.

Partial dopamine agonism

Acts as a partial agonist at D2 receptors—stabilizing dopamine activity by activating receptors when dopamine is too low and competing with excess dopamine when it's too high, producing more balanced neurotransmitter regulation.

Serotonin modulation

Also acts as a partial agonist at 5-HT1A receptors and an antagonist at 5-HT2A receptors, contributing to its effectiveness for depression and anxiety symptoms alongside its antipsychotic action.

Favorable tolerability profile

Less likely than many antipsychotics to cause significant weight gain, sedation, or metabolic changes—making it a preferred option for long-term maintenance treatment in conditions like bipolar disorder and schizophrenia.

Virtual visit with clinician

Ongoing support, always available.

You’ll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.

Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we’ll manage dosing and monitor for side effects. If lab testing is recommended, we review results and refine your plan accordingly. You’re never left to navigate care on your own.

All your care in one place. That’s the General Medicine difference.

We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way. It’s comprehensive care that looks at the full picture — your goals, your history, your lifestyle — and makes it simple to move forward with confidence.

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What our customers have to say

“I feel like I’m finally on the right path to improving my health with the right support now! It’s so refreshing and reassuring.”

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“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

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Get the care you need, without the wait.

Frequently Asked Questions

How long before Abilify starts working?

For acute mania or psychosis, some symptom improvement may appear within the first week. For depression as an add-on treatment or for maintenance in bipolar disorder, full benefit may take 4–6 weeks.

Is Abilify weight-neutral compared to other antipsychotics?

Aripiprazole has a more favorable metabolic profile than many other atypical antipsychotics — it's less likely to cause significant weight gain, elevated blood sugar, or lipid abnormalities that are common concerns with long-term use.

Can I stop Abilify on my own?

No. Stopping antipsychotic medication abruptly can trigger withdrawal symptoms and increase the risk of symptom relapse — especially for schizophrenia and bipolar disorder. Always taper under your clinician's supervision.

What side effects might I experience?

Restlessness (akathisia), nausea, insomnia, headache, and dizziness are most common. Aripiprazole is less likely to cause drowsiness than many other antipsychotics, which some people find an advantage.

Is Abilify safe for use in adolescents?

Yes. Aripiprazole is approved for schizophrenia and bipolar disorder in adolescents aged 13–17, and for irritability associated with autism spectrum disorder in children aged 6 and older.
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