Zyvox

Brand for Linezolid

Without insurance

With insurance

Compare prices at 50K+ pharmacies nationwide

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Zyvox?

Zyvox is a prescription oxazolidinone antibiotic used to treat serious infections caused by gram-positive bacteria, including MRSA (methicillin-resistant Staphylococcus aureus), vancomycin-resistant Enterococcus (VRE), and drug-resistant pneumococcal pneumonia. It's one of the few oral antibiotics that achieves blood levels comparable to IV administration, making it a rare option for outpatient treatment of serious resistant infections. Zyvox works through a unique mechanism distinct from all other antibiotic classes, meaning bacteria resistant to other drugs rarely show pre-existing resistance to it. Duration of use is typically limited due to the risk of bone marrow suppression.

Unique 50S ribosomal binding

Binds to the 23S ribosomal RNA of the 50S subunit at a site distinct from all other antibiotics, blocking the formation of the ribosomal initiation complex and preventing the start of bacterial protein synthesis—a mechanism that bypasses existing antibiotic resistance.

MRSA and VRE activity

Effective against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus—two of the most difficult-to-treat resistant pathogens—providing treatment options when most other antibiotics have failed.

Oral bioequivalence to IV

Zyvox's oral formulation achieves blood levels nearly identical to IV administration, enabling treatment of serious drug-resistant infections in outpatient settings and facilitating hospital-to-home transitions without compromising therapeutic efficacy.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

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—Nika, Tennessee

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