General MedicineGeneral Medicine
Trazodone

Trazodone

Without insurance

With insurance

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is trazodone?

Trazodone is an antidepressant that is now most commonly prescribed at lower doses for insomnia — particularly for people who struggle to fall asleep or stay asleep. At the doses used for sleep, its sedating properties take center stage, while its antidepressant effects become more relevant at higher doses. It works by affecting serotonin and histamine receptors in the brain. Unlike many sleep medications, trazodone is not classified as a controlled substance and doesn't carry the same risk of dependence, making it a frequently chosen option for longer-term sleep support.

Serotonin and histamine modulation

Blocks certain serotonin receptors and histamine receptors in the brain, producing sedation and reducing the hyperarousal that prevents restful sleep — without the dependency profile of benzodiazepines or Z-drugs.

Non-addictive sleep support

Because trazodone is not a controlled substance, it can be used more freely for chronic sleep difficulties without the prescribing restrictions or dependency concerns associated with traditional sedative-hypnotics.

Dual-purpose flexibility

At lower doses it functions primarily as a sleep aid. At higher doses it acts as a full antidepressant — giving prescribers flexibility to address both mood and sleep within a single medication when both are present.

Virtual visit with clinician

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

5 out of 5 stars on Trustpilot

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

5 out of 5 stars on Trustpilot

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

5 out of 5 stars on Trustpilot

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

5 out of 5 stars on Trustpilot

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

5 out of 5 stars on Trustpilot

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

5 out of 5 stars on Trustpilot

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

5 out of 5 stars on Trustpilot

Frequently asked questions

What is General Medicine?

What can General Medicine help with?

How much does General Medicine cost?

Who is the care team at General Medicine?

How do you protect my health information?