Sitagliptin

Generic for Januvia

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Most insurance accepted

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Available nationwide

What is sitagliptin?

Sitagliptin is a DPP-4 inhibitor used to improve blood sugar control in adults with Type 2 diabetes. It works by blocking the enzyme that breaks down incretin hormones — GLP-1 and GIP — allowing these natural hormones to remain active longer and stimulate insulin release in a glucose-dependent manner. This means sitagliptin only promotes insulin secretion when blood sugar is elevated, significantly reducing the risk of hypoglycemia compared to older diabetes medications. It's taken once daily as a tablet and is weight-neutral, making it a well-tolerated addition to existing diabetes regimens.

DPP-4 enzyme inhibition

Blocks dipeptidyl peptidase-4, the enzyme that rapidly degrades GLP-1 and GIP incretin hormones, extending their activity and allowing them to stimulate more insulin release and suppress glucagon in a glucose-dependent manner.

Glucose-dependent insulin stimulation

Because it works through incretin hormones that only activate insulin release when blood sugar is elevated, sitagliptin carries a low risk of hypoglycemia — unlike sulfonylureas that stimulate insulin regardless of current glucose levels.

Weight-neutral profile

Unlike some diabetes medications that cause weight gain, sitagliptin has a neutral effect on body weight — an important consideration for Type 2 diabetes management where excess weight is often a contributing factor.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

4.7 stars from 550+ reviews

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

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