Silvadene

Brand for silver sulfadiazine

Without insurance

With insurance

Compare prices at 50K+ pharmacies nationwide

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Silvadene?

Silvadene is a prescription topical antimicrobial cream used to prevent and treat bacterial and fungal infections in people with second and third degree burns. It combines the antimicrobial properties of silver with the antibiotic activity of sulfadiazine, providing broad-spectrum coverage against the wide range of organisms that can colonize burn wounds. Applied directly to the burn surface and covered with a dressing once or twice daily, it helps keep the wound clean and infection-free during the critical healing period. It also provides a moist wound environment that supports tissue healing.

Dual silver and sulfonamide antimicrobial action

Silver ions disrupt bacterial cell membrane function and inhibit enzyme activity through multiple simultaneous mechanisms, while sulfadiazine blocks folate synthesis — providing broad-spectrum antibacterial and antifungal coverage across the diverse pathogens that threaten burn wounds.

Broad burn wound coverage

Effective against gram-positive bacteria, gram-negative bacteria including Pseudomonas aeruginosa, and Candida yeast — addressing the full spectrum of organisms that colonize and infect serious burns during the vulnerable healing period.

Moist wound environment support

The cream base maintains appropriate wound moisture that supports epithelialization and healing, while the antimicrobial activity protects against the infection that is the primary cause of morbidity in people with serious burns.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

4.7 stars from 550+ reviews

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

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