Relpax

Brand for Eletriptan

Without insurance

With insurance

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Most insurance accepted

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Available nationwide

What is Relpax?

Relpax is a second-generation triptan medication taken at the onset of a migraine to stop the attack. It works by activating serotonin 5-HT1B and 5-HT1D receptors, causing constriction of dilated cranial blood vessels and blocking the release of inflammatory neuropeptides from trigeminal nerve endings that drive migraine pain. Compared to first-generation triptans, Relpax has a higher receptor affinity and better oral bioavailability, which may translate to faster and more reliable relief for some patients. It's taken as a single tablet and a second dose can be taken if the migraine returns after initial relief.

High-affinity serotonin receptor activation

Binds with greater affinity to 5-HT1B and 5-HT1D receptors than older triptans, producing potent cranial vasoconstriction and blocking the trigeminal inflammatory cascade that sustains migraine pain.

Improved oral bioavailability

Relpax's pharmacokinetic profile—with higher oral bioavailability than sumatriptan—results in more consistent drug absorption and potentially more reliable migraine relief across different patients and migraine types.

Second-dose option

If the migraine returns after initial relief, a second dose can be taken 2 hours after the first—providing a practical option for migraines that initially respond but subsequently recur within the same attack.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

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