Periogard

Brand for chlorhexidine

Without insurance

With insurance

Compare prices at 50K+ pharmacies nationwide

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Periogard?

Periogard is a prescription antiseptic oral rinse containing Periogard, used to treat gingivitis — inflammation of the gums caused by bacterial plaque. It's typically prescribed following dental procedures or for people with significant gum disease to reduce the bacterial load in the mouth and allow gum tissue to heal. Chlorhexidine works by disrupting bacterial cell membranes, killing the bacteria responsible for plaque and gum inflammation. It's used twice daily as a rinse for 30 seconds — not swallowed — and may cause temporary tooth staining and altered taste with extended use.

Bacterial membrane disruption

Chlorhexidine binds to negatively charged bacterial cell walls and membranes, disrupting their integrity and causing bacterial cell death—reducing the plaque-forming bacteria responsible for gingivitis.

Substantivity advantage

Chlorhexidine adheres to oral tissues and continues releasing antibacterial activity for hours after rinsing—a property called substantivity—providing longer-lasting bacterial suppression than standard antiseptic rinses.

Post-procedural gum healing

By significantly reducing oral bacterial burden, Periogard creates a cleaner environment for gum tissue to heal after dental procedures or during treatment of periodontitis—complementing mechanical cleaning and professional dental care.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

4.7 stars from 550+ reviews

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

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