Nucala

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Compare prices at 50K+ pharmacies nationwide

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Nucala?

Nucala is a biologic injection used as an add-on maintenance treatment for severe eosinophilic asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and hypereosinophilic syndrome. It works by targeting interleukin-5 (IL-5)—the cytokine primarily responsible for the growth, activation, and survival of eosinophils, the white blood cells that drive eosinophilic inflammation. By blocking IL-5, Nucala dramatically reduces circulating and tissue eosinophil counts, decreasing the underlying inflammation that causes severe asthma attacks and organ damage in eosinophilic conditions. It's given as a subcutaneous injection once every four weeks.

IL-5 cytokine blockade

Binds to and neutralizes interleukin-5, the primary growth and survival factor for eosinophils—preventing IL-5 from binding to its receptor on eosinophil progenitors and mature cells, dramatically reducing eosinophil production and survival.

Eosinophil count reduction

Clinical trials showed reductions in blood eosinophil counts of greater than 80% with Nucala—directly reducing the tissue eosinophilia responsible for airway inflammation in severe asthma and organ involvement in EGPA.

Asthma exacerbation prevention

By controlling the eosinophilic inflammation driving severe asthma, Nucala significantly reduces the frequency of severe asthma attacks and the need for oral corticosteroid rescue courses—improving quality of life and reducing long-term steroid burden.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

4.7 stars from 550+ reviews

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

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